A. Results on HEIRO™ documented at the State of Pennsylvania Animal Diagnostic Laboratory System (PADLS) on December 12, 2008. All electrolyte/mineral levels reported as SAFE. Actual levels of these important elements in HEIRO™ as follows:

		Report Date:      12/12/2008
	HEIRO™	Laboratory Maximum Tolerance Level Index of Animal Health
ppm Calcium	4,930 - Safe	20,000
ppm Colbalt	<0.2 - Safe	25
ppm Copper	3.23- Safe	250
ppm Iron	144 - Safe	500
ppm Magnesium	6,360 - Safe	8,000
ppm Phosphorus	935- Safe	10,000
ppm Potassium	3,800 - Safe	10,000
ppm Selenium	<1.0- Safe	5
ppm Sodium	2,790 - Safe	N/A
ppm Zinc	51.9 - Safe	500

Heiro shows you actual lab tests for safety and purity - more than any other supplement.

Heiro has the advantage of having a low iron level similar to grass hay. Some doctors are studying high iron possibly causing insulin problems, so Heiro is the choice for a tested safe low iron insulin supplement.

Heiro is using organics to provide natural, powerful, and safe minerals.

B.   Equi-Analytical Laboratories - the top commercial feed testing lab in the country. Results show low sugar (ESC) and low starch so it is SAFE. Results show a protein level of grass hay and a non-fiber carbohydrate (NFC) in the normal range of beet pulp. Results show a HUGE Vitamin E amount that comes to over 8,000 IU/oz. That is, by far, the best level of any supplement. The test results confirm the significant levels of ten (10) electrolytes and minerals.

HEIRO™ has been tested extensively for safety and content.

	Date Reported:  12/08/08
% Moisture		12.6
% Dry Matter		87.4
	Dry Matter
Digestible Energy (DE), Mcal/lb		2.33
	%	g/lb.
Crude Protein	7.9	35.6
Acid Detergent Fiber (ADF)	19.2	87.3
Neutral Detergent Fiber (NDF)	18.7	85.0
ESC (Simple Sugars)	3.8	17.1
Starch	0.5	2.2
Non Fiber Carb. (NFC)	30.7	0.0
Water Soluble Carb. (WSC)	4.7	21.3
	%	g/lb.
Calcium	0.47	2.14
Phosphorus	0.17	0.78
Magnesium	0.69	3.13
Potassium	0.47	2.13
Sodium	0.309	1.401
	ppm	mg/lb.
Iron	118	54
Zinc	32	15
Copper	4	2
Manganese	23	10
Molybdenum	2.1	0.95
	100% Dry
Vitamin E, IU/Lb.	128,190

III.   What Is Not In HEIRO™?

1. HEIRO™ is not cooked or processed - at times you will actually see the entire seed of the herb in HEIRO™. Cooking takes vitamins/minerals out.
2. Unsafe amounts of unknown items - HEIRO's™ herbs are USDA Certified Organic and double-lab tested for content and safety. In 2000, the State of California Department of Health Services put out a warning that five (5) Chinese herbal mixtures for Diabetes contained two (2) pharmaceutical drugs. Vet. Practice News, May 2006.
3. No fillers - this is why you only give one (1) tablespoon a day.
4. Not a diluted tea - again, vitamins and minerals are lost.
5. No sugar additives - HEIRO™ is the only supplement tested to be low in sugar and starch. Our starch is only 0.5% and our simple sugar is only 3.8%.
6. No artificial flavors or preservatives. No artificial colors. All natural.
7. No untested, unknown sources of herbs. Heiro™ contains only the best, top rated, 100% USDA Certified Organic Herbs. There is no finer source of herbs for people or horses. USDA Certified Organic means no ionizing radiation, no genetically-engineered product, grown without pesticides or petroleum-based/sewage sludge fertilizers. Radiated or sludge-borne herbs are allowed with other herbals.
8. No lead- state lab certified.
9. No pesticides- state lab certified.
10. No melamine- state lab certified.
11. No drugs- state lab certified.
    In today's world of tainted dog and cat foods and baby formula, you need to know Heiro™ is safe.

IV. What are the signs of Insulin Resistance?

1.   Laminitis – acute or chronic.  Repeat episodes over the years, pasture turnout stopped but still happens, secondary to Cushings disease, more often in ponies, occurs in the middle of the winter when there is no grass around. The horse only gets hay and no grain and still happens.
2.   Overweight – either by diet, lack of exercise, or genetics.  25% of people with Insulin Resistance due to genetics.  On no grain or little grain and stays big, exercise and still big. Cresty neck often seen.
3.   Cushings – 2 ways Insulin Resistance is linked with Cushings.

a.   Many with diagnosed Cushings also have Insulin Resistance but this second condition is not diagnosed, so on Pergolide but still does not do well.
b.   Recent study shows Cushings in horses is massively under diagnosed, so if these are missed, then more are missed with both Cushings and Insulin Resistance.

4. Age – as horses get older, they lose muscle and gain fat.  Fat production goes way up in Insulin Resistance because Insulin makes fat and fat produces toxins leading to an increase in Insulin. Also as horses age, Cushings incidence goes up.
5. Fatigue – can not exercise as well as in the past.  They become dull and resist riders.
6. Certain Breeds- Breeds that were designed for a rugged existence seem to be more susceptible due to today's easier surroundings. These breeds include Quarter Horses, Morgans, Paso Finos, Mustangs, Pony breeds, Tennessee Walkers, and Rocky Mountain Horses.
7. Genetics- The National Institute of Health (NIH) has shown a genetic trait in Insulin Resistance. Often the mare or stallion had Insulin Resistance and now the offspring start to show signs.
8. History behind the horse- The previous owner warns the new owner that the animal must live on a dirt lot and never be turned out. They are the horses who are fed very little food and stay "fat on air". Some times Pergolide helped in the past but is no longer effective.
9. Winter Foot Pain - Even with no grass in sight, the feet get sore. Less exercise, loss of fresh grass, vitamins/magnesium, cold stress, cortisol increase, seasonal ACTH increase, longer fasting periods between food intake all contribute.
10. Abnormally foot sore after routine trimmings by Farrier. Takes several days after scheduled trimmings to recover soundness. This is an Insulin problem not a bad trim job. The Farrier is the key to a successful program.



 

Genetic lock- diet/exercise is not controlling insulin. Owners have tried multiple management techniques but the horse is still foot sore, has repeat laminitis, can't be turned out on grass, and stays big on little food. Also the horse is a candidate for future problems and the owner would like to avoid a problem instead of waiting for the problem to occur. These are the horses the Heiro program can help.

V.      What Is Insulin Resistance?

1.   Abnormally high Insulin levels cause metabolic changes leading to increased fat, overweight, fatigue, and eventually Laminitis.
 2.   Why high Insulin?  Inability to respond and use Insulin the body produces because the Insulin is not functioning properly; higher and higher Insulin levels are needed to achieve the same effect.  These high levels of Insulin damage the body.

The Heiro™ Program is like no other -- correct way to test, best diet and snacks, a testable supplement, and free veterinary consults. Other products are "here's a powder, good luck to you".

VI.    Why Laminitis in Insulin Resistance?
          Several ways:

1.   Insulin itself – at high levels can damage vessels.  A recent Australian study showed that giving a horse a shot of Insulin causes profound Laminitis clinically and microscopically. K. Asplin, Australian Government Rural Industries Research, November 2007.
2.  A University of Kentucky study shows that inflammatory proteins elevate when the horse has Insulin

LAMINITIS

Resistance and this irritates blood vessels leading to blood flow disruption to feet. A. Adams, J. An. Sci., 2007, Vol. 85.
3.  Insulin Resistance results in both reduced capillary recruitment and reduced vasodilation in animal models and in humans. Diabetes Vascular Disease Research 2007, Microcirculation Journal 2007.
4.  "Although pro-inflammatory effects and vascular effects of Insulin Resistance may be difficult to separate, it is clear that either or both occurring in horses with Insulin Resistance could precipitate Laminitis by affecting blood flow or by induction of pro-inflammatory state." Dr. McGowan, Journal of Equine Science 2008.
5.  Extreme cases – if hyperglycemic, this promotes inflammatory medicators leading to irritated blood vessels.
6.  First time considered as a possible cause of Laminitis by Dr. Reilly – Foot Neuropathy. In diabetic people, nerves to feet become desensitized – if in a horse, could have Laminitis but not know of damage as readily.  If the horse shows no pain, Laminitis spreads until critical.  We do not get a warning.  Why a possible?  70,000 foot amputations a year in the USA of Insulin Resistance/Diabetic people.
7.   Overweight – all these problems compounded by the stress of high weight.

VII.    How to Test?  Testing procedures are discussed in depth in our Insulin Resistance Article. 

Therapeutic Diagnosis - For a variety of reasons, some owners can not get the Insulin blood level of their horse. In these cases, cleints will try Heiro™ for sixty (60) days to seehow it helps their horse. The owner diagnoses the problem of Insulin Resistance by gauging how the horse responds to Heiro™.

 

For further information, on Insulin Resistance go to Article section for the following in depth discussion:

• What is Insulin and Insulin Resistance?
• Exercise
• Chromium, Magnesium, Pergolide, Thyroid powder and Metformin
• Diet: Best Hay, Grain, and Amounts
• Pasture Turnout and the Best Muzzle
• Good and bad snacks, Horse Treats
• Avoiding Glucosamine
• Feeding Flax Seed
• Lyme Disease
• How to correctly test for Insulin Resistance
• Glucose-Insulin Ratio (why not the best test)
• Diagnostic Results for Insulin Resistance
• Farrier Schedule/Foot Trimming/Best Glue On Shoe
• Vaccines
• Pasture Management for Insulin Resistant Horses
• Winter Foot Pain
• Results

 

To order Heiro™, go to the Order Form section.

Click Here For 2011 updated information and Articles On Insulin Resistance

Proper diet and exercise is essential for horse health. HEIRO™ is a supplement to help maintain horse health. This product is not intended to diagnose, treat, cure, or prevent disease.

 

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